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Multiple factors affect HIV prognosis, study shows

February 5, 2013 - In a major advancement for the field of HIV treatment, a new study has identified a more accurate method of suggesting prognosis for HIV patients.

The new method, called the Veterans Aging Cohort Study index, takes into account factors such as hemoglobin level, platelet count and comorbidity. Previous models of predicting HIV-related outcomes depended only on levels of CD4, a glycoprotein found on the surface of immune system T-cells, and viral load, an estimate of the amount of virus present in the body. But as improved antiretroviral therapy has lengthened the life expectancy of HIV patients, these two factors are no longer sufficient in developing a patient's prognosis, said Amy Justice, a professor at the Yale School of Medicine and chief of general internal medicine for the VA Connecticut Healthcare System.

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