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April 24, 2024
1 step closer to a cure
CRISPR-Cas Gene Editing ‘Completely’ Eliminated HIV in Cell Culture
By IDSE News Staff
A team of researchers in the Netherlands said the latest CRISPR-Cas gene editing technology can be used to eliminate all traces of HIV from infected cells in the laboratory, raising hopes for a cure, according to a study that will be detailed at ESCMID Global 2024 (formerly ECCMID), which runs April 27-30, in Barcelona, Spain.
The studies present a significant breakthrough in the search for an HIV cure, according to Elena Herrera-Carrillo, PhD, an associate professor in the Department of Medical Microbiology, Laboratory of Experimental Virology, University of Amsterdam Medical Center (abstracts P0004, P0006, P0013, P0026 and P0004).
CRISPR-Cas gene editing technology allows for precise alterations to the genomes of living organisms. This revolutionary technique enables scientists to accurately target and modify specific segments of an organism’s genetic code. Functioning like molecular “scissors” with the guidance of guide RNA (gRNA), CRISPR-Cas can cut the DNA at designated spots. This action facilitates either the deletion of unwanted genes or introduction of new genetic material into an organism’s cells, paving the way for advanced therapies.
Continue reading... https://www.idse.net/HIV-AIDS-STIs/Article/04-24/CRISPR-Cas-HIV-Cure-Hope/73565
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