The International AIDS Society (IAS) announces a new grant of £500,000 from ViiV Healthcare to support its Collaborative Initiative for Paediatric HIV Education and Research (CIPHER)
Thursday, 6 March 2014 (Geneva, Switzerland) - Following on from a first generous grant for £1,500,000
received from ViiV Healthcare in 2012, the IAS's Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) has
received a second grant for £500,000. Thanks to this, the IAS will utilize this funding to strengthen and extend its activities
in paediatric HIV to include priority areas of advocacy and implementation of programmes for scale-up of optimized care and
"In recent years much progress has been made in scaling up prevention of mother-to-child transmission (PMTCT) and increasing
the number of children on antiretroviral therapy (ART). Despite these efforts, the paediatric population remains understudied in
comparison with adults," said Bernard Kadasia, Acting Executive Director of the IAS. "Thanks to the support of ViiV Healthcare,
we believe that our CIPHER initiative, by promoting and investing in paediatric research, and by strengthening paediatric
cohort collaboration, will help to address critical research gaps related to clinical management and delivery of service
to infants, children and adolescent affected by HIV in resource-limited settings".
The announcement by researchers at yesterday´s Conference on Retroviruses and Opportunistic Infections (CROI) in Boston,
that a second baby is currently HIV free after early treatment soon after birth, together with the US federal government funded study
of around 60 babies that is just getting under way, are clear indications that paediatric HIV research is gaining strong momentum.
The new ViiV grant will strengthen CIPHER's programme for 2014 and 2015 and allow for extending the scope of the
initiative. Specifically, the grant will fund the CIPHER Research Grant Programme; the global CIPHER Cohort
Collaboration, Online Paediatric HIV Cohort Database launched
in December 2013; and a stakeholder consultation in early 2015
"Efforts to scale up HIV treatment and care services for children have intensified; however, access to appropriate treatment
and care for this population remains a major unmet need in HIV. In the light of this, Paediatric HIV remains an important priority for
ViiV Healthcare - so I am really proud to be making this announcement today as part of our Paediatric Innovation Seed Fund."
Commented Dr Dominique Limet, CEO, ViiV Healthcare.
Founded in 2012, the CIPHER Grant Programme was established with the support of ViiV Healthcare to encourage research projects
that have the potential to address priority research questions and in its first year granted a total of USD$ 1 million to seven high-level
research projects. The strategy for 2014 will be to grant, for a maximum of USD$ 150,000 per project, two additional grants that could
not be funded in 2013.
The CIPHER Cohort Collaboration is a global collaboration of paediatric HIV cohorts that will be looking at
two critical research gaps in paediatric HIV: the durability of first-line antiretroviral treatment (ART) in children in resource-limited
settings; and the global epidemiology of adolescents living with HIV since birth. CIPHER is providing a grant of USD$500,000 to fund
these two important projects, the first to include such a broad range of participating paediatric cohorts.
The CIPHER Paediatric HIV Cohort Database, launched on World AIDS Day 2013, features an interactive map and
complete cohort profiles and is designed to act as a forum and tool for researchers, funders and policy makers. It is intended to act as
a dedicated platform for communication and coordination, facilitating harmonization of protocols, data collection, sharing and
analysis between cohorts.
In 2014, this core programme will be built upon, while engaging with partners to develop potential new activities in key areas
of advocacy and implementation of programmes for scale-up of care and services for paediatric populations.
Finally, in 2015 all CIPHER's stakeholders (researchers, policy and decision makers, industry representatives) will meet to
take stock of the achievements, discuss ways to optimize the programme results and brainstorm CIPHER's future directions.
About CIPHER: Promoting and investing in targeted research to address knowledge gaps/priority questions to optimize service delivery and clinical management of infants and children in resource-limited settings.
The Collaborative Initiative for Paediatric HIV Education and Research
(CIPHER) is a flagship paediatric research initiative of the International AIDS Society (IAS), aimed at addressing outstanding
research gaps related to clinical management and delivery of services to infants, children and adolescents affected by HIV in
resource-limited settings. Initiated in 2012, CIPHER is supported by an unrestricted grant from ViiV Healthcare's
Paediatric Innovation Seed Fund. The content and structure of the project is guided by paediatric experts convened by the IAS.
The main objectives of CIPHER are:
Convening stakeholders and establishing collaboration mechanisms to strengthen communication, knowledge transfer and exchange among paediatric HIV cohorts
CIPHER is designed to complement existing global initiatives and create partnerships with other organizations to maximize investment in paediatric HIV research and improve paediatric health outcomes. The first phase of the project consisted of building a solid scientific and programmatic foundation. A comprehensive needs assessment was conducted, including a literature review and key informant interviews with experts, which outlined a set of research priorities that has been used to inform and guide CIPHER.
About the IAS:
The International AIDS Society (IAS) is the world's leading independent association of HIV professionals, with over 16,000 members from
more than 196 countries working at all levels of the global response to AIDS. The IAS members include researchers from all disciplines,
clinicians, public health and community practitioners on the frontlines of the epidemic, as well as policy and programme planners.
The IAS is lead organizer of the IAS Conference on HIV Pathogenesis, Treatment and Prevention, which will be held in Kuala Lumpur,
Malaysia, 30 June – 3 July 2013 and custodian of the biennial International AIDS Conference, which will be held in Melbourne,
Australia, 20-25 July 2014. www.iasociety.org | www.ias2013.org | www.aids2014.org
For more information:
Siân Bowen (Geneva, Switzerland)
Senior Manager, Communications
Tel: +41 22 710 0864
US Mob (July 16-28): +1 202 997 6935
Francesca Da Ros (Geneva, Switzerland)
IAS Senior Coordinator, Communications and Media
Tel: +41 22 710 0822
Mob: +41 796 109679
US Mob (July 16-28): +1 202 997 6917
Source: International AIDS Society
"Reproduced with permission - International AIDS Society"
International AIDS Society
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