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Emerging Diseases

Pediatric Hepatitis of Unknown Origin Cases Mounting

14% Received Liver Transplants; 5 Deaths Reported

By Marie Rosenthal, MS

MAY 6, 2022—About half the country is seeing hepatitis of unknown origin cases among children that might be caused by adenovirus type 41F.

The CDC is investigating possible cases in 109 children from 25 states and territories. Fourteen percent of the children required liver transplants, and five deaths have been reported, according to Jay Butler, MD, the deputy director for Infectious Diseases at the CDC, who provided an update on the emerging disease on May 6. 

The first cases were reported among nine children in Alabama in October 2021. “All of the patients were previously healthy, came from different parts of the state and were hospitalized with significant liver injury without a known cause, including some with acute liver failure,” Dr. Butler said. “All nine ultimately tested positive for adenovirus, which is a common virus that typically causes mild cold or flu-like symptoms or stomach and intestinal problems.”

Continue reading... https://www.idse.net/Emerging-Diseases/Article/05-22/Pediatric-Hepatitis-of-Unknown-Origin-Cases-Mounting/66928


"Reproduced with permission - Infectious Disease Special Edition (IDSE)"

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