 |
| |
|

|
Prevalence of non-communicable diseases among people living with HIV at HIV Clinic of Kigali University Teaching hospital (CHUK), a cross-sectional study
Scientific Reports (2026) Cite this article
Abstract
The introduction of highly active antiretroviral therapy prolonged the life span of PLWHIV and therefore; they live longer and develop chronic diseases, which are associated with ageing related Non-Communicable Diseases. The study aimed to assess the prevalence of non-communicable diseases and associated risk factors among people living with HIV infection at a Tertiary Hospital of Rwanda. A cross-sectional study was conducted to PLWHIV followed at the ambulatory HIV clinic of Kigali University Teaching hospital (CHUK) from August 2019 to Feb 2020, A systematic random sampling approach was used to select participants from the clinic registry. Social-demographic data, psychometric and clinical data were collected using structured questionnaire. Anthropometric and biochemical measurements were performed and results were recorded using Epidata and exported to SPSS for analysis. Logistic regression analysis was used to explore associated risk factors. A total of 222 participants were enrolled from a cohort of 2580 PLWH in care. The overall prevalence of NCDs was 36%. The most common condition was hypertension 22.5%), Diabetes mellitus 9.9%, renal impairment 9.9%, and dyslipidemia 3.2%. Among these NCDs, a high proportion were newly identified cases: 80% for hypertension, 41% for diabetes, and 54% for renal impairment. The most frequent comorbidities were hypertension with renal impairment (35% of comorbid cases), and hypertension with diabetes (30%). Factors independently associated with NCDs included Age above 65years [AOR: 8.3;95%CI:2.3–30, P < 0.001],; physical inactivity [AOR:2.1,95%CI:1.1–3.8, P = 0.013]; adverse drug reaction 50% [AOR:2.2; 95%CI: 1.2–4.1, P = 0.009]. Non- communicable diseases are highly prevalent in PLWHIV, with Hypertension, Diabetes, and renal failure being the most common. A substantial proportion of cases remained. Old age, Physical inactivity, and adverse effect to drugs were significant predictors of NCDs in this population. These findings highlight the need of integrating NCDs screening and management within HIV care services.
Abbreviations
- CHUK:
-
Kigali University Teaching hospital
- CKD:
-
Chronic kidney disease
- CVD:
-
Cardiovascular diseases
- DM:
-
Diabetes mellitus
- HbA1C:
-
Glycated hemoglobin
- HDL:
-
High Density Lipoprotein
- HIV:
-
Human immunodeficiency virus
- HIVAN:
-
HIV associated nephropathy
- HTN:
-
Hypertension
- LDL-C:
-
Low density lipoprotein cholesterol
- NCD:
-
non communicable disease
- NRTI:
-
Nucleoside reverse transcriptase inhibitors
- Open MRS:
-
Open Medical Record System
- PLWHIV:
-
People Living with HIV
- SD:
-
Standard Deviation
- SPSS:
-
Statistical Package for Social Sciences
- TC:
-
Total Cholesterol
- USA:
-
United States of America
- VL:
-
Viral load
- WHO:
-
World health organization
Ethics declarations
Competing interests
The authors declare no competing interests.
Ethics approvals
This research was conducted by respecting ethical standards according to the Declaration of Helsinki (1964). The permission to conduct this study was obtained from the research and ethics committee of university of Rwanda [CMHS/IRB/129/2019] and University Teaching Hospital of Kigali [EC/CHUK/085/2019] and Institutional review board (IRB) [139/CMHS IRB/2019]. Data collectors out of health facilities of interest were trained on study participants’ rights, confidentiality and ethical norms. Written informed consents were obtained from all study participants before starting the interview, and data were anonymously collected. For participants aged below 18 years, informed consent was obtained from a parent and/or legal guardian in addition to the participant’s own assent. The privacy and confidentiality of the study participants were ensured throughout and after the study. No benefits for study participants. Study participants were informed that there was no risk of withdrawal from the study.
Rights and permissions
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.
Reprints and permissions
About this article
Cite this article
Turikumwe, S., Nyampinga, D., Dukundane, A. et al. Prevalence of non-communicable diseases among people living with HIV at HIV Clinic of Kigali University Teaching hospital (CHUK), a cross-sectional study. Sci Rep (2026). https://doi.org/10.1038/s41598-026-57403-7
Download citation
This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
Source: Nature
https://www.nature.com/articles/s41598-026-57403-7
For more HIV and AIDS News visit…
Back to…
Positively Positive - Living with HIV/AIDS: HIV/AIDS News
For more HIV and AIDS News visit…
Positively Positive - Living with HIV/AIDS: HIV/AIDS News Archive
|
…positive attitudes are not simply ‘moods’
Copyright © 2003 - 2026 Bradford McIntyre. All rights reserved.
DESIGNED TO CREATE HIV & AIDS AWARENESS
|
 |
|