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New Enterprise-OCTAVE Workshop for Young and Early Career Investigators

Statistical Methods in HIV Vaccine Trial Design and Evaluation

11-12 September 2011 Bangkok, Thailand (prior to AIDS Vaccine 2011)

June 11, 2011 - The Global HIV Vaccine Enterprise and the OCTAVE Project (Online Collaborative Training for AIDS Vaccine Evaluation), in close collaboration with the HIV Vaccine Trials Network (HVTN) and the Statistical Center for HIV/AIDS Research & Prevention (SCHARP), is soliciting applications for a workshop for young and early-career investigators (YECIs) focused on key statistical considerations for the design and analysis of early and late stage vaccine trials.

The HIV vaccine field has entered a new phase of discovery as we probe correlates of protection from a partially effective vaccine regimen evaluated in Thailand, explore novel antibodies capable of neutralizing a majority of circulating viral strains and design new trials to evaluate a variety of different vaccine concepts.  This multi-disciplinary learning opportunity, which blends online and face-to-face learning, features global experts in HIV trial design, including core faculty from Emmes, the HVTN and SCHARP.  The workshop will allow participants to:

  • Review fundamental statistical and clinical trial design concepts relevant to vaccine evaluation;
  • Understand the activities of Data Safety and Monitoring Boards;
  • Describe findings from RV144 and explore the approach to define and evaluate correlates of vaccine protection;
  • Describe adaptive trial designs and how they may be used to evaluate the efficacy of multiple vaccine regimens in parallel;
  • Consider study designs that aim to evaluate combination HIV prevention strategies (e.g., vaccines and ARV-based prevention strategies).

Since 2004, OCTAVE has developed learning opportunities for YECIs that incorporate eLearning and interactive, face-to-face workshops. A customized web-portal will allow YECIs to access up-to-date learning resources in advance of the workshop on 29 - 30 June 2011 in New York, NY USA.

We encourage highly qualified early-career investigators, statisticians and epidemiologists (within 10 years of completing their terminal degree/training program) to submit an online application here

To apply, you will need to submit a CV, a statement of interest and a letter of recommendation from an institutional or organizational official, supervisor, or colleague verifying your eligibility and merit to participate in this workshop. The deadline for applications is 24 June 2011 . In your statement of interest, please describe your research interests and how this workshop will support your future work in the HIV vaccine field. Notifications on the application status will be sent out by Friday, 15 July 2011. Participants need to be available to take part in a pre-orientation webinar on 1 or 2 August 2011.

Twenty-five to 30 scholars will be selected. Air travel, ground transportation, hotel accommodations for the workshop and the AIDS Vaccine 2011 conference, as well as registration to AIDS Vaccine 2011 will be provided through the workshop.

This workshop is supported by the NIH Office of AIDS Research. The Capacity-Building Series is a program of the Global HIV Vaccine Enterprise, a unique alliance of independent organizations around the world dedicated to accelerating the development of a preventive HIV vaccine.

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